On Wednesday, the coalition urged voters to reject Issue 5 for a number of reasons.
"It is an inferior medicine compared to other choices," said Dr. David Smith, a physician who specializes in pain relief.
He gave his primary reason for opposing medical marijuana.
"The so called 'Medical Marijuana' is not a scientifically validated way to relieve pain or suffering," Dr. Smith said, "Addictive drugs must be carefully regulated and controlled by our FDA, the DEA and trained pharmacists."
Following Wednesday's meeting, THV had the chance to ask the coalition of doctor's what's the single greatest reason why they oppose legalizing medical marijuana.
Their response: lack of controls.
Dr. Smith stated there is one FDA-approved ingredient of marijuana that doctors can prescribe. It's known as the Marinol Pill. Its active ingredient is THC, the primary psychoactive element of marijuana.
"That one has been purified, we know what's in it. We know the best indications, we know the limitations, we know the side effects. And we know what we're getting when we prescribe it to a patient," Dr. Smith said.
Gary and Melissa Fults representing Arkansans for Compassionate Care attended the physician's coalition's meeting Wednesday, holding up signs in disagreement.
"Pain doctors, their job is to administer pain medicine to them. Think of the thousands of dollars that they make off of pain medication," Gary Fults said.
Smith said he disagrees.
"The biggest threat is when you've got something that's evidence based that costs less. Yeah that's a threat. But we're a long way because the studies just haven't been done," Dr. Smith added.
Whatever the side Arkansans take, they alone will have the final say on legalizing medical marijuana on November 6th.
While this physician coalition opposes legalizing medical marijuana, Arkansans for Compassionate Care said there are around 70 Arkansas doctors are supporting the measure.
However, they said the majority of their doctor supporters are afraid to speak up for fear of losing their jobs.